RT Book, Section A1 Ritter, Kathryn A1 Fitch, Robert Warne A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181043601 T1 Subclavian Vein Thrombosis T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessmedicine.mhmedical.com/content.aspx?aid=1181043601 RD 2024/03/29 AB Thrombosis of the subclavian vein (Paget–von Schrötter syndrome) is an uncommon condition, typically occurring in young patients following exercise and compression injury to the subclavian or axillary vein from a narrow thoracic outlet (effort thrombosis). Pain, tightness, and arm swelling are manifest within a day. Pitting edema develops in the fingers, hand, and forearm. There is no arterial insufficiency, and the pulses are palpable. This syndrome is separate from iatrogenic upper extremity thrombosis, generally as a result of vascular access catheters. There is a 15% risk of developing pulmonary embolism from thrombosis of upper extremity veins; however, large or fatal emboli are very rare. Ultrasound has become the screening test of choice. Superior vena cava syndrome, upper extremity trauma, heart failure, angioedema, and lymphatic obstruction are in the differential.