RT Book, Section A1 Ritter, Kathryn A1 Fitch, Robert Warne A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181043513 T1 Necrotizing Fasciitis T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessmedicine.mhmedical.com/content.aspx?aid=1181043513 RD 2024/04/24 AB This uncommon, severe infection involves the subcutaneous soft tissues, including the superficial and deep fascial layers. It is usually seen in the lower extremities, abdominal wall, and perianal or groin area. It is commonly spread from a trauma site, surgical wound, abscess, or decubitus ulcer. Alcoholism, parenteral drug abuse, and diabetes are predisposing factors. Pain, tenderness, erythema, swelling, warmth, shiny skin, lymphangitis, and lymphadenitis are early findings. Later, there is rapid progression of bullae with clear pink or purple fluid and cutaneous necrosis; the skin becomes anesthetic, and subcutaneous gas may be present. Systemic toxicity may be manifest by fever, dehydration, leukocytosis, and frequently positive blood cultures. Type I is polymicrobial and includes anaerobic species. Type II includes group A streptococci.