RT Book, Section A1 Effron, David A1 Forcier, Beverly C. A1 Wyszynski, Richard E. A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181039674 T1 Cytomegalovirus Retinitis T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessmedicine.mhmedical.com/content.aspx?aid=1181039674 RD 2023/09/24 AB Patients may complain of the gradual and usually painless onset of the following visual sensations: floaters, scintillating scotomas (quivering blind spots), decreased peripheral visual field, and metamorphopsia (wavy distortion of vision). Cytomegalovirus (CMV) infiltrates appear as focal, small (but may be larger, confluent) white lesions in the retina that look like cotton wool spots. CMV is a necrotizing virus that is spread hematogenously, so that damage is concentrated in the retina adjacent to the major vessels and the optic disk. Often hemorrhage is involved with significant retinal necrosis (dirty white with a granular appearance), giving the “pizza pie” or “cheese and ketchup” appearance. Optic nerve involvement and retinal detachments can be present.