RT Book, Section A1 Singh, Manpreet A1 Whitfield, Denise A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181038169 T1 Osteogenesis Imperfecta T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessmedicine.mhmedical.com/content.aspx?aid=1181038169 RD 2024/10/10 AB Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder. The disease manifests on a spectrum with patients with more severe disease often suffering from fractures with minimal or no trauma. Very severe forms of disease can result in perinatal death. OI manifests most commonly as excess or atypical fractures, but other findings include short statures, hearing loss, easy bruising, and a scleral tint with the sclerae commonly appearing blue.