RT Book, Section
A1 Aster, Jon C.
A1 Bunn, H. Franklin
SR Print(0)
ID 1175525742
T1 Hemostasis and Thrombosis: Introduction
T2 Pathophysiology of Blood Disorders, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9781259642067
LK accessmedicine.mhmedical.com/content.aspx?aid=1175525742
RD 2024/04/16
AB Hemostasis  commands  special  attention  among  both  physicians  and  investigators.  The  importance  and  appeal  of  this  discipline  rests  on  exciting  scientific  advances  as  well  as  its  obvious  clinical  relevance.  The  mechanisms  underlying  the  initiation  and  control  of  blood  coagulation  constitute  an  elaborate  and  beautifully  integrated  system  of  cellular  and  molecular  interactions  that  fulfill  a  biological  function  of  crucial  importance.  As  summarized  in  Chapter  1,  the  circulation  of  blood  cells  and  plasma  through  the  vascular  tree  is  essential  for  providing  the  body’s  organs  and  tissues  with  nutrients  and  oxygen  and  for  defense  against  infection  and  inflammation.  Platelets,  endothelial  cells,  and  coagulation  proteins  cooperate  in  a  complex  and  dynamic  way  to  repair  leaks  in  the  vasculature  and  protect  against  hemorrhage  in  a  high-pressure  circulatory  system.