RT Book, Section
A1 Smollin, Craig
A1 Olson, Kent R.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
SR Print(0)
ID 1175794856
T1 Poisoning or Overdose–Related Hyperthermia
T2 Current Medical Diagnosis & Treatment 2021
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260469868
LK accessmedicine.mhmedical.com/content.aspx?aid=1175794856
RD 2022/06/30
AB Hyperthermia  may  be  associated  with  poisoning  by  amphetamines  and  other  synthetic  stimulants  (cathinones,  piperazines),  atropine  and  other  anticholinergic  drugs,  cocaine,  salicylates,  strychnine,  2,4-dinitrophenol,  tricyclic  antidepressants,  and  various  other  medications.  Overdoses  of  serotonin  reuptake  inhibitors  (eg,  fluoxetine,  paroxetine,  sertraline)  or  their  use  in  a  patient  taking  an  MAO  inhibitor  may  cause  agitation,  hyperactivity,  myoclonus,  and  hyperthermia  (“serotonin  syndrome”).  Antipsychotic  agents  can  cause  rigidity  and  hyperthermia  (neuroleptic  malignant  syndrome  [NMS]).  (See  section  on  schizophrenia  and  other  psychotic  disorders  in  Chapter  25.)  Malignant  hyperthermia  is  a  rare  disorder  associated  with  general  anesthetic  agents.