RT Book, Section A1 Philip, Susan S. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1175788015 T1 Syphilis: Course & Prognosis T2 Current Medical Diagnosis & Treatment 2021 YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260469868 LK accessmedicine.mhmedical.com/content.aspx?aid=1175788015 RD 2023/02/02 AB The lesions associated with primary and secondary syphilis are self-limiting, even without treatment, and resolve with few or no residua. Ocular and otologic syphilis have been associated with permanent vision and hearing loss. Tertiary and congenital syphilis may be highly destructive and permanently disabling and may lead to death. While infection is almost never completely eradicated in the absence of treatment, most infections likely remain latent without sequelae, and only a small number of latent infections progress to further disease.