RT Book, Section A1 Dirkx, Tonja C. A1 Woodell, Tyler B. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1177463047 T1 Nephrogenic Systemic Fibrosis T2 Current Medical Diagnosis & Treatment 2021 YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260469868 LK accessmedicine.mhmedical.com/content.aspx?aid=1177463047 RD 2023/02/07 AB Nephrogenic systemic fibrosis is a multisystem disorder seen only in patients with CKD (primarily with an eGFR less than 15 mL/min/1.73 m2, but rarely with a GFR of 15–29 mL/min/1.73 m2), AKI, and after kidney transplantation. Histopathologically, there is an increase in dermal spindle cells positive for CD34 and procollagen I. Collagen bundles with mucin and elastic fibers are also noted.