RT Book, Section
A1 Dirkx, Tonja C.
A1 Woodell, Tyler B.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
SR Print(0)
ID 1177463047
T1 Nephrogenic Systemic Fibrosis
T2 Current Medical Diagnosis & Treatment 2021
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260469868
LK accessmedicine.mhmedical.com/content.aspx?aid=1177463047
RD 2021/02/28
AB Nephrogenic  systemic  fibrosis  is  a  multisystem  disorder  seen  only  in  patients  with  CKD  (primarily  with  an  eGFR  less  than  15  mL/min/1.73  m2,  but  rarely  with  a  GFR  of  15–29  mL/min/1.73  m2),  AKI,  and  after  kidney  transplantation.  Histopathologically,  there  is  an  increase  in  dermal  spindle  cells  positive  for  CD34  and  procollagen  I.  Collagen  bundles  with  mucin  and  elastic  fibers  are  also  noted.