RT Book, Section A1 Gasper, Warren J. A1 Iannuzzi, James C. A1 Johnson, Meshell D. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1175799726 T1 Acute Mesenteric Vein Occlusion T2 Current Medical Diagnosis & Treatment 2021 YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260469868 LK accessmedicine.mhmedical.com/content.aspx?aid=1175799726 RD 2023/02/08 AB The hallmarks of acute mesenteric vein occlusion are postprandial pain and evidence of a hypercoagulable state. Acute mesenteric vein occlusion presents similarly to the arterial occlusive syndromes but is much less common. Patients at risk include those with paroxysmal nocturnal hemoglobinuria; protein C, protein S, or antithrombin deficiencies; or the JAK2 mutation. These lesions are difficult to treat surgically, and thrombolysis is the mainstay of therapy. Aggressive long-term anticoagulation is required for these patients.