RT Book, Section
A1 Benowitz, Neal L.
A2 Olson, Kent R.
A2 Anderson, Ilene B.
A2 Benowitz, Neal L.
A2 Blanc, Paul D.
A2 Clark, Richard F.
A2 Kearney, Thomas E.
A2 Kim-Katz, Susan Y.
A2 Wu, Alan H. B.
SR Print(0)
ID 1174605046
T1 ANTIDEPRESSANTS, TRICYCLIC
T2 Poisoning & Drug Overdose, 7e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071839792
LK accessmedicine.mhmedical.com/content.aspx?aid=1174605046
RD 2024/10/12
AB Tricyclic  antidepressants  taken  in  overdose  by  suicidal  patients  are  a  substantial  cause  of  poisoning  hospitalizations  and  deaths.  Currently  available  tricyclic  antidepressants  are  described  in  Table  II–8.  Amitriptyline  also  is  marketed  in  combination  with  chlordiazepoxide  (Limbitrol)  or  perphenazine  (Etrafon  or  Triavil).  Cyclobenzaprine  (Flexeril),  a  centrally  acting  muscle  relaxant,  is  structurally  related  to  the  tricyclic  antidepressants  but  exhibits  minimal  cardiotoxic  and  variable  CNS  effects.  Newer,  noncyclic  antidepressants  are  discussed  on  Antidepressants,  General  (Noncyclic)  are  discussed  on  Monoamine  Oxidase  Inhibitors.