RT Book, Section
A1 Benowitz, Neal L.
A2 Olson, Kent R.
A2 Anderson, Ilene B.
A2 Benowitz, Neal L.
A2 Blanc, Paul D.
A2 Clark, Richard F.
A2 Kearney, Thomas E.
A2 Kim-Katz, Susan Y.
A2 Wu, Alan H. B.
SR Print(0)
ID 1174605030
T1 ANTIDEPRESSANTS, GENERAL (NONCYCLIC)
T2 Poisoning & Drug Overdose, 7e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071839792
LK accessmedicine.mhmedical.com/content.aspx?aid=1174605030
RD 2024/04/16
AB Many  noncyclic  antidepressants  are  available.  These  can  be  classified  as  selective  serotonin  reuptake  inhibitors  (SSRIs),  including  fluoxetine  (Prozac),  sertraline  (Zoloft),  citalopram  (Celexa),  escitalopram  (Lexapro),  paroxetine  (Paxil),  and  fluvoxamine  (Luvox);  serotonin-norepinephrine  reuptake  inhibitors  (SNRIs),  including  venlafaxine  (Effexor),  desvenlafaxine  (Pristiq)  duloxetine  (Cymbalta),  milnacipran  (Savella)  and  levomilnacipran  (Fetzima);  norepinephrine-dopamine  reuptake  inhibitors  (NDRIs),  including  bupropion  (Wellbutrin);  and  others,  including  trazodone  (Desyrel)  and  mirtazapine  (Remeron),  the  latter  a  tetracyclic  antidepressant.  Bupropion  is  also  marketed  under  the  brand  name  Zyban  for  smoking  cessation.  In  overdose  these  drugs  are  generally  less  toxic  than  the  tricyclic  antidepressants  and  the  monoamine  oxidase  (MAO)  inhibitors,  although  serious  effects,  such  as  seizures,  hypotension,  cardiac  arrhythmias,  and  serotonin  syndrome,  occasionally  occur.  Noncyclic  and  tricyclic  antidepressants  are  described  in  Table  II–8.