RT Book, Section A1 Berkowitz, Aaron L. SR Print(0) ID 1174547663 T1 Extraocular Movements and Approach to Diplopia: Cranial nerves 3, 4, and 6 T2 Clinical Neurology and Neuroanatomy: A Localization-Based Approach YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259834400 LK accessmedicine.mhmedical.com/content.aspx?aid=1174547663 RD 2024/03/28 AB Each eye is moved by six muscles: four rectus muscles and two oblique muscles. These muscles are controlled by three nerves: cranial nerves (CNs) 3, 4, and 6. These cranial nerves all originate from brainstem nuclei that communicate with one another through the medial longitudinal fasciculus (MLF) to coordinate movements between the left and right eyes. These nuclei are controlled by brainstem gaze centers that coordinate the eyes to move together horizontally or vertically, and these gaze centers are stimulated by cortical eye fields. From the top down, the cortical eye fields stimulate the gaze centers in the brainstem, the brainstem gaze centers communicate with the cranial nerve nuclei of CN 3, CN 4, and CN 6, and CN3, CN 4, and CN 6 activate the extraocular muscles.