RT Book, Section A1 Mahon, Joseph A1 McVary, Kevin T. A2 Bhasin, Shalender A2 O’Leary, Michael P. A2 Basaria, Shehzad S. SR Print(0) ID 1174516269 T1 Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia T2 Essentials of Men’s Health YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781260135886 LK accessmedicine.mhmedical.com/content.aspx?aid=1174516269 RD 2024/04/19 AB Benign prostatic hyperplasia (BPH) and benign prostatic hypertrophy are often incorrectly used interchangeably. BPH is a histological diagnosis defined as an increase in the total number of prostatic stromal cells and prostatic glandular epithelial cells within the transition zone. As a result of this hyperplasia, large, discrete, prostatic nodules can develop. Benign prostatic hypertrophy, on the other hand, is defined as an increase in the size of the individual prostatic cells resulting in a global enlargement of the prostate gland with no discrete nodularity. Through a combination of these two processes, benign prostatic enlargement (BPE) results. If BPE leads to obstruction of the bladder neck in the absence of prostate cancer, benign prostatic obstruction (BPO) results.