RT Book, Section A1 Levinson, Warren A1 Chin-Hong, Peter A1 Joyce, Elizabeth A. A1 Nussbaum, Jesse A1 Schwartz, Brian SR Print(0) ID 1171927888 T1 Sepsis & Septic Shock T2 Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e YR 2020 FD 2020 PB McGraw Hill PP New York, NY SN 9781260116717 LK accessmedicine.mhmedical.com/content.aspx?aid=1171927888 RD 2024/04/19 AB Sepsis is one of the leading causes of morbidity and mortality in the United States. Centers for Disease Control and Prevention (CDC) estimates that more than 1.7 million adults in America develop sepsis each year. Sepsis and septic shock cause approximately 270,000 deaths annually, have fatality rates of 30% to 50% in older patients, and are estimated to cost more than 30 billion dollars each year. The incidence of infections that result in sepsis continues to rise with the increased incidence of antibiotic-resistant organisms along with the increased use of immunosuppressive drugs, intravenous and urinary catheters, and prosthetic implants.