RT Book, Section A1 Levinson, Warren A1 Chin-Hong, Peter A1 Joyce, Elizabeth A. A1 Nussbaum, Jesse A1 Schwartz, Brian SR Print(0) ID 1171926486 T1 Adaptive Immunity: B Cells & Antibodies T2 Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e YR 2020 FD 2020 PB McGraw Hill PP New York, NY SN 9781260116717 LK accessmedicine.mhmedical.com/content.aspx?aid=1171926486 RD 2024/04/19 AB B cells perform two important functions: (1) they differentiate into plasma cells that produce antibodies and (2) they differentiate into long-lasting memory cells that respond robustly and rapidly to reinfection. Antibodies are the principal defense used by the immune system to prevent infection because, by binding to the microbes’ surfaces, they can inhibit them from attaching to target cells and/or recruit innate immune killing mechanisms. Antibodies can also inhibit toxins such as those made by tetanus and diphtheria. Nearly all vaccines are designed to generate these protective, or neutralizing, antibodies.