RT Book, Section
A1 Lyu, Heather G.
A1 Clancy, Thomas E.
A2 Doherty, Gerard M.
SR Print(0)
ID 1171279698
T1 Pancreas
T2 Current Diagnosis & Treatment: Surgery, 15e
YR 2020
FD 2020
PB McGraw Hill LLC
PP New York, NY
SN 9781260122213
LK accessmedicine.mhmedical.com/content.aspx?aid=1171279698
RD 2024/04/25
AB The  pancreas  appears  in  the  fourth  week  of  fetal  life  from  the  caudal  part  of  the  foregut  as  dorsal  and  ventral  pancreatic  buds.  Both  buds  rotate  to  the  right  and  fuse  near  the  point  of  origin  of  the  ventral  pancreas.  Later,  as  the  duodenum  rotates,  the  pancreas  shifts  to  the  left.  In  the  adult,  only  the  caudal  portion  of  the  head  and  the  uncinate  process  are  derived  from  the  ventral  pancreas.  The  cranial  part  of  the  head  and  all  of  the  body  and  tail  are  derived  from  the  dorsal  pancreas.  Most  of  the  dorsal  pancreatic  duct  joins  with  the  duct  of  the  ventral  pancreas  to  form  the  main  pancreatic  duct  (duct  of  Wirsung);  a  small  part  persists  as  the  accessory  duct  (duct  of  Santorini).  In  5%-10%  of  people,  the  ventral  and  dorsal  pancreatic  ducts  do  not  fuse,  a  condition  known  as  pancreatic  divisum,  and  most  regions  of  the  pancreas  drain  through  the  duct  of  Santorini  and  the  orifice  of  the  minor  papilla.  In  this  case,  only  the  small  ventral  pancreas  drains  with  the  common  bile  duct  through  the  papilla  of  Vater.