RT Book, Section
A1 Lee, Brian K.
A1 Vincenti, Flavio G.
A2 McAninch, Jack W.
A2 Lue, Tom F.
SR Print(0)
ID 1171185610
T1 Chronic Kidney Disease and Renal Replacement Therapy
T2 Smith & Tanagho's General Urology, 19e
YR 2020
FD 2020
PB McGraw Hill
PP New York, NY
SN 9781259834332
LK accessmedicine.mhmedical.com/content.aspx?aid=1171185610
RD 2024/04/19
AB In  chronic  kidney  disease  (CKD),  reduced  clearance  of  certain  solutes  principally  excreted  by  the  kidney  results  in  their  retention  in  the  body  fluids.  The  solutes  are  end  products  of  endogenous  metabolism  as  well  as  exogenous  substances  (eg,  drugs).  The  most  commonly  measured  indicators  of  renal  failure  are  blood  urea  nitrogen  (BUN)  and  serum  creatinine.  The  renal  clearance  of  creatinine  (as  calculated  from  a  24-hour  urine  collection)  is  often  used  as  a  surrogate  measure  of  glomerular  filtration  rate  (GFR).