RT Book, Section A1 McDonald, Michelle L. A1 Kane, Christopher J. A2 McAninch, Jack W. A2 Lue, Tom F. SR Print(0) ID 1171185078 T1 Disorders of the Adrenal Glands T2 Smith & Tanagho's General Urology, 19e YR 2020 FD 2020 PB McGraw Hill PP New York, NY SN 9781259834332 LK accessmedicine.mhmedical.com/content.aspx?aid=1171185078 RD 2024/04/25 AB The adrenal cortex is composed of three zones with distinct endocrine functions: zona glomerulosa (produces mineralocorticoids), zona fasciculata (produces glucocorticoids), and zona reticularis (produces sex steroids). The adrenal medulla accounts for approximately 10% of the gland and is composed of chromaffin cells that secrete catecholamines. Disturbances to the hypothalamic–pituitary–adrenal axis (Figure 31–1) result in classic endocrine disorders such as Cushing’s syndrome, hyperaldosteronism, and catechol excess from pheochromocytoma (see Tables 31–1 and 31–2). The diagnosis of these disorders requires careful endocrine and radiographic evaluation.