RT Book, Section
A1 Hoffman, Barbara L.
A1 Schorge, John O.
A1 Halvorson, Lisa M.
A1 Hamid, Cherine A.
A1 Corton, Marlene M.
A1 Schaffer, Joseph I.
SR Print(0)
ID 1171662685
T1 Endometrial Cancer
T2 Williams Gynecology, 4e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260456868
LK accessmedicine.mhmedical.com/content.aspx?aid=1171662685
RD 2024/04/18
AB In  the  United  States,  endometrial  cancer  is  the  most  common  gynecologic  malignancy.  Risk  factors  include  obesity  and  advancing  age.  As  these  factors  are  now  more  prevalent,  the  incidence  of  endometrial  cancer  continues  to  rise.  Fortunately,  patients  usually  seek  medical  attention  early  due  to  vaginal  bleeding,  and  endometrial  biopsy  leads  quickly  to  diagnosis.  The  cornerstone  of  treatment  is  hysterectomy  with  bilateral  salpingo-oophorectomy  (BSO)  and  surgical  staging  that  includes  lymph  node  assessment  for  most  women.  Of  affected  women,  67  percent  will  have  stage  I  disease  that  is  potentially  curable  by  surgery  alone,  although  high-risk  stage  I  patients  often  receive  adjuvant  therapy  (Siegel,  2019).  The  21  percent  of  patients  with  regional  disease  and  8  percent  with  distant  disease  typically  require  multimodality  treatment  that  includes  some  combination  of  surgery,  chemotherapy,  and  radiotherapy.