RT Book, Section
A1 Jameson, J. Larry
A1 Fauci, Anthony S.
A1 Kasper, Dennis L.
A1 Hauser, Stephen L.
A1 Longo, Dan L.
A1 Loscalzo, Joseph
SR Print(0)
ID 1167069632
T1 Vaccines
T2 Harrison's Manual of Medicine, 20e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455342
LK accessmedicine.mhmedical.com/content.aspx?aid=1167069632
RD 2024/04/19
AB Vaccines  are  unrivaled  in  the  twenty-first  century  for  their  effects  on  longevity,  economic  savings,  and  quality  of  life.–  Although  most  vaccines  developed  in  the  twentieth  century  targeted  common  acute  infectious  diseases  of  childhood,  more  recently  developed  vaccines  prevent  chronic  conditions  prevalent  among  adults  (e.g.,  human  papillomavirus  vaccines  for  cervical  and  anogenital  cancers,  herpes  zoster  vaccine).Seventeen  diseases  are  now  preventable  through  vaccines  routinely  administered  in  the  United  States,  and  rates  of  vaccine-preventable  diseases  of  childhood  are  at  historic  lows.Vaccines  protect  the  immunized  individual  (a  direct  effect).  Many  also  confer  herd  immunity  (an  indirect  effect),  in  which  transmission  of  infections  to  unimmunized  populations  is  reduced.Immunization  programs  are  associated  with  controlling,  eliminating,  or  eradicating  a  disease.–  Smallpox  is  the  only  human  infection  to  be  eradicated,  although  ongoing  efforts  are  targeting  the  global  eradication  of  polio.The  Centers  for  Disease  Control  and  Prevention  (CDC)  Advisory  Committee  on  Immunization  Practices  (ACIP)  makes  recommendations  for  the  administration  of  vaccines  approved  by  the  FDA  for  use  in  children  and  adults  (Fig.  206-1).–  Pregnant  women  and  immunocompromised  pts  should  not  receive  live-virus  vaccines.Administering  immunizations  to  adults  involves  a  number  of  processes,  such  as  deciding  whom  to  vaccinate,  assessing  vaccine  contraindications  and  precautions,  providing  vaccine  information  statements  (VISs),  ensuring  appropriate  storage  and  handling  of  vaccines,  administering  vaccines,  and  maintaining  vaccine  records.