RT Book, Section
A1 Jameson, J. Larry
A1 Fauci, Anthony S.
A1 Kasper, Dennis L.
A1 Hauser, Stephen L.
A1 Longo, Dan L.
A1 Loscalzo, Joseph
SR Print(0)
ID 1167069616
T1 Cocaine and Other Commonly Used Drugs
T2 Harrison's Manual of Medicine, 20e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455342
LK accessmedicine.mhmedical.com/content.aspx?aid=1167069616
RD 2024/04/25
AB Stimulants  and  hallucinogens  have  been  used  to  induce  euphoria  and  alter  consciousness  for  centuries.  Cocaine  and  marijuana  are  two  of  the  most  commonly  used  drugs  today.  Polydrug  use  involving  concurrent  use  of  several  drugs  with  different  pharmacologic  effects  is  increasingly  found.  Sometimes  one  drug  is  used  to  enhance  the  effects  of  another,  as  with  the  combined  use  of  cocaine  and  nicotine,  or  cocaine  and  heroin  in  methadone-maintained  pts.  Some  forms  of  polydrug  use,  such  as  the  combined  use  of  IV  heroin  and  cocaine,  are  especially  dangerous  and  account  for  many  hospital  ER  visits.  Chronic  drug  use  is  associated  with  immune  system  dysfunction  and  increased  vulnerability  to  infections,  including  risk  for  HIV  infection.  The  concurrent  use  of  cocaine  and  opiates  (“speedball”)  is  frequently  associated  with  needle  sharing  by  people  using  drugs  intravenously.