RT Book, Section
A1 Jameson, J. Larry
A1 Fauci, Anthony S.
A1 Kasper, Dennis L.
A1 Hauser, Stephen L.
A1 Longo, Dan L.
A1 Loscalzo, Joseph
SR Print(0)
ID 1167068476
T1 Amyloidosis
T2 Harrison's Manual of Medicine, 20e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455342
LK accessmedicine.mhmedical.com/content.aspx?aid=1167068476
RD 2024/04/24
AB Amyloidosis  is  a  term  for  a  group  of  protein  misfolding  disorders  characterized  by  the  extracellular  deposition  of  insoluble  polymeric  protein  fibrils  in  tissues  and  organs.  Clinical  manifestations  depend  on  anatomic  distribution  and  intensity  of  amyloid  protein  deposition;  they  range  from  local  deposition  with  little  significance  to  involvement  of  virtually  any  organ  system  with  severe  pathophysiologic  consequences.