RT Book, Section A1 Jameson, J. Larry A1 Fauci, Anthony S. A1 Kasper, Dennis L. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Loscalzo, Joseph SR Print(0) ID 1167068343 T1 Vasculitis T2 Harrison's Manual of Medicine, 20e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455342 LK accessmedicine.mhmedical.com/content.aspx?aid=1167068343 RD 2024/04/23 AB A clinicopathologic process characterized by inflammation of and damage to blood vessels, compromise of vessel lumen, and resulting ischemia. Clinical manifestations depend on size and location of affected vessel. Most vasculitic syndromes appear to be mediated by immune mechanisms. May be primary or sole manifestation of a disease or secondary to another disease process. Unique vasculitic syndromes can differ greatly with regards to clinical features, disease severity, histology, and treatment.