RT Book, Section
A1 Jameson, J. Larry
A1 Fauci, Anthony S.
A1 Kasper, Dennis L.
A1 Hauser, Stephen L.
A1 Longo, Dan L.
A1 Loscalzo, Joseph
SR Print(0)
ID 1167068181
T1 Systemic Lupus Erythematosus
T2 Harrison's Manual of Medicine, 20e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455342
LK accessmedicine.mhmedical.com/content.aspx?aid=1167068181
RD 2024/04/24
AB Disease  of  unknown  etiology  in  which  tissues  and  cells  undergo  damage  mediated  by  tissue-binding  autoantibodies  and  immune  complexes.  Genetic,  environmental,  and  sex  hormonal  factors  are  likely  of  pathogenic  importance.  T-  and  B-cell  hyperactivity,  production  of  autoantibodies  with  specificity  for  nuclear  antigenic  determinants,  and  abnormalities  of  T-cell  function  occur.