RT Book, Section A1 Jameson, J. Larry A1 Fauci, Anthony S. A1 Kasper, Dennis L. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Loscalzo, Joseph SR Print(0) ID 1167067450 T1 Dialysis T2 Harrison's Manual of Medicine, 20e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455342 LK accessmedicine.mhmedical.com/content.aspx?aid=1167067450 RD 2023/05/30 AB The decision to initiate dialysis for the management of end-stage renal disease (ESRD) usually depends on a combination of the pt’s symptoms, comorbid conditions, and laboratory parameters. Unless a living donor is identified, transplantation is deferred by necessity, due to the scarcity of deceased donor organs (median waiting time, 3–6 years at most transplant centers). Dialytic options include hemodialysis and peritoneal dialysis (PD). Roughly 85% of U.S. pts are started on hemodialysis. All three forms of “renal replacement therapy” (RRT) require planning and preparation months to years before ESRD occurs; early referral to a nephrologist is thus critical for successful RRT.