RT Book, Section A1 Jameson, J. Larry A1 Fauci, Anthony S. A1 Kasper, Dennis L. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Loscalzo, Joseph SR Print(0) ID 1167062733 T1 Hypoxic-Ischemic Encephalopathy T2 Harrison's Manual of Medicine, 20e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455342 LK accessmedicine.mhmedical.com/content.aspx?aid=1167062733 RD 2024/04/18 AB Results from lack of delivery of oxygen to the brain because of extreme hypotension or respiratory failure. Most common causes are myocardial infarction (MI), cardiac arrest, shock, asphyxiation, paralysis of respiration, and carbon monoxide or cyanide poisoning. In some circumstances, hypoxemia may predominate. Carbon monoxide and cyanide poisoning are termed histotoxic hypoxemia because they cause a direct impairment of the respiratory chain.