RT Book, Section A1 Jameson, J. Larry A1 Fauci, Anthony S. A1 Kasper, Dennis L. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Loscalzo, Joseph SR Print(0) ID 1167062679 T1 Stroke T2 Harrison's Manual of Medicine, 20e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455342 LK accessmedicine.mhmedical.com/content.aspx?aid=1167062679 RD 2024/03/28 AB Sudden onset of a neurologic deficit from a vascular mechanism: ∼85% are ischemic; ∼15% are primary hemorrhages (subarachnoid [Chap. 20] and intraparenchymal). An ischemic deficit that resolves rapidly without radiologic evidence of an infarction is termed a transient ischemic attack (TIA); 24 h is a commonly used boundary between TIA and stroke, although most TIAs last between 5 and 15 min. Stroke is a leading cause of neurologic disability in adults; ∼150,000 deaths annually in the United States. Much can be done to limit morbidity and mortality through prevention and acute intervention.