RT Book, Section
A1 Blaha, Michael J.
A1 Baron, Robert B.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
SR Print(0)
ID 1166616010
T1 Secondary Conditions that Affect Lipid Metabolism
T2 Current Medical Diagnosis and Treatment 2020
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455281
LK accessmedicine.mhmedical.com/content.aspx?aid=1166616010
RD 2022/05/26
AB Several  factors,  including  drugs,  can  influence  serum  lipids  (eTable  28–1).  These  are  important  for  two  reasons:  abnormal  lipid  levels  (or  changes  in  lipid  levels)  may  be  the  presenting  sign  of  some  of  these  conditions,  and  correction  of  the  underlying  condition  may  obviate  the  need  to  treat  an  apparent  lipid  disorder.  Thyroid  disease,  particularly  hypothyroidism,  is  associated  with  a  high  LDL.  Poorly  controlled  diabetes  mellitus  and  alcohol  use,  in  particular,  are  commonly  associated  with  high  triglyceride  levels  that  decline  with  improvements  in  glycemic  control  or  reduction  in  alcohol  use,  respectively.  Thus,  secondary  causes  of  high  blood  lipids  should  be  considered  in  each  patient  with  a  lipid  disorder  before  lipid-lowering  therapy  is  started.  In  most  instances,  special  testing  is  not  needed:  a  history  and  physical  examination  are  sufficient.