RT Book, Section A1 Dirkx, Tonja C. A1 Woodell, Tyler A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1166171060 T1 Nephrogenic Systemic Fibrosis T2 Current Medical Diagnosis and Treatment 2020 YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455281 LK accessmedicine.mhmedical.com/content.aspx?aid=1166171060 RD 2022/05/27 AB Nephrogenic systemic fibrosis is a multisystem disorder seen only in patients with CKD (primarily with an eGFR less than 15 mL/min/1.73 m2, but rarely with a GFR of 15–29 mL/min/1.73 m2), AKI, and after kidney transplantation. Histopathologically, there is an increase in dermal spindle cells positive for CD34 and procollagen I. Collagen bundles with mucin and elastic fibers are also noted.