RT Book, Section A1 Anker, Naomi B. A1 Cho, Kerry C. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1166170372 T1 Normal Anion Gap Acidosis T2 Current Medical Diagnosis and Treatment 2020 YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455281 LK accessmedicine.mhmedical.com/content.aspx?aid=1166170372 RD 2022/05/16 AB The two major causes are gastrointestinal HCO3– loss and defects in renal acidification (renal tubular acidosis) (Table 21–15). The urinary anion gap can differentiate between these causes.