RT Book, Section
A1 Smollin, Craig
A1 Olson, Kent R.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
SR Print(0)
ID 1166176681
T1 Petroleum Distillates & Solvents Poisoning
T2 Current Medical Diagnosis and Treatment 2020
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260455281
LK accessmedicine.mhmedical.com/content.aspx?aid=1166176681
RD 2022/05/19
AB Petroleum  distillate  toxicity  may  occur  from  inhalation  of  the  vapor  or  as  a  result  of  pulmonary  aspiration  of  the  liquid  during  or  after  ingestion.  Acute  manifestations  of  aspiration  pneumonitis  are  vomiting,  coughing,  and  bronchopneumonia.  Some  hydrocarbons—ie,  those  with  aromatic  or  halogenated  subunits—can  also  cause  severe  systemic  poisoning  after  oral  ingestion.  Hydrocarbons  can  also  cause  systemic  intoxication  by  inhalation.  Vertigo,  muscular  incoordination,  irregular  pulse,  myoclonus,  and  seizures  occur  with  serious  poisoning  and  may  be  due  to  hypoxemia  or  the  systemic  effects  of  the  agents.  Chlorinated  and  fluorinated  hydrocarbons  (trichloroethylene,  Freons,  etc)  and  many  other  hydrocarbons  can  cause  ventricular  arrhythmias  due  to  increased  sensitivity  of  the  myocardium  to  the  effects  of  endogenous  catecholamines.