RT Book, Section A1 Chesnutt, Asha N. A1 Chesnutt, Mark S. A1 Prendergast, Niall T. A1 Prendergast, Thomas J. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. SR Print(0) ID 1166164911 T1 Mediastinal Masses T2 Current Medical Diagnosis and Treatment 2020 YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260455281 LK accessmedicine.mhmedical.com/content.aspx?aid=1166164911 RD 2022/05/20 AB Various developmental, neoplastic, infectious, traumatic, and cardiovascular disorders may cause masses that appear in the mediastinum on chest radiograph. A useful convention arbitrarily divides the mediastinum into three compartments—anterior, middle, and posterior—in order to classify mediastinal masses and assist in differential diagnosis. Specific mediastinal masses have a predilection for one or more of these compartments; most are located in the anterior or middle compartment. The differential diagnosis of an anterior mediastinal mass includes thymoma, teratoma, thyroid lesions, lymphoma, and mesenchymal tumors (lipoma, fibroma). The differential diagnosis of a middle mediastinal mass includes lymphadenopathy, pulmonary artery enlargement, aneurysm of the aorta or innominate artery, developmental cyst (bronchogenic, enteric, pleuropericardial), dilated azygous or hemiazygous vein, and foramen of Morgagni hernia. The differential diagnosis of a posterior mediastinal mass includes hiatal hernia, neurogenic tumor, meningocele, esophageal tumor, foramen of Bochdalek hernia, thoracic spine disease, and extramedullary hematopoiesis. The neurogenic tumor group includes neurilemmoma, neurofibroma, neurosarcoma, ganglioneuroma, and pheochromocytoma.