RT Book, Section
A1 Long, Brit
A1 Koyfman, Alex
A2 Tintinalli, Judith E.
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Stapczynski, J. Stephan
A2 Cline, David M.
A2 Thomas, Stephen H.
SR Print(0)
ID 1167031819
T1 The Transplant Patient
T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260019933
LK accessmedicine.mhmedical.com/content.aspx?aid=1167031819
RD 2024/04/19
AB Organ  transplantation  is  growing  in  frequency,  with  the  first  successful  kidney  transplant  in  the  early  1950s.1,2  As  of  the  beginning  of  2013,  there  were  76,047  active  candidates  waiting  for  solid-organ  transplants  in  the  United  States,  with  the  kidney  transplant  waitlist  being  the  largest  at  57,903  candidates.3  The  kidney  is  the  most  commonly  transplanted  organ  (58%),  followed  by  liver  (21%),  heart  (8%),  lung  (5%),  pancreas  (5%),  and,  less  commonly,  combined  organ  transplants  and  intestine  transplants.  Annually,  there  are  approximately  18,000  hematopoietic  stem  cell  transplants  in  the  United  States,  with  about  one  third  of  these  transplants  being  allogenic  transplants  and  two  thirds  being  autologous  transplants.4  The  recent  opioid  epidemic  has  produced  several  challenges  for  the  transplant-awaiting  population.  The  increase  in  opioid-related  deaths  has  led  to  an  increase  in  the  number  of  available  organs;  however,  the  risk  of  infection  from  opioid-related  donor  organs  is  slightly  higher  than  from  non–opioid  substance  user  donors.  The  U.S.  Public  Health  Service  states  that  organs  obtained  from  opioid  abusers  are  at  slightly  increased  risk  of  infection,  although  recent  data  suggest  these  organs  can  be  safely  used  for  transplant.  Potential  recipients  also  may  suffer  from  addiction,  which  is  associated  with  worse  outcomes  with  transplantation.5