RT Book, Section A1 Slattery, David E. A1 Pollack, Jr, Charles V. A2 Tintinalli, Judith E. A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Stapczynski, J. Stephan A2 Cline, David M. A2 Thomas, Stephen H. SR Print(0) ID 1166813100 T1 Thrombotics and Antithrombotics T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260019933 LK accessmedicine.mhmedical.com/content.aspx?aid=1166813100 RD 2024/10/10 AB Antithrombotic therapy (i.e., anticoagulants, antiplatelet agents, and fibrinolytics) is used to treat or reduce the risk of arterial and venous thromboembolic conditions, including acute coronary syndrome, deep venous thrombosis and pulmonary embolism (collectively, venous thromboembolic disease), transient ischemic attack, and ischemic stroke (Table 239-1). Moreover, antithrombotic agents help prevent occlusive vascular events in patients at risk for thrombosis due to atherosclerotic arterial disease, atrial fibrillation, medical illness with immobility, or surgical insult. These agents, however, can cause life-threatening complications, primarily serious or life-threatening hemorrhage. Detailed management strategies for thromboembolic disorders are discussed in their respective chapters (see Chapter 49, “Acute Coronary Syndromes”; Chapter 56, “Venous Thromboembolism Including Pulmonary Embolism”; and Chapter 167, “Stroke Syndromes”).