RT Book, Section A1 Hosmer, Kathleen A1 Miller, Chadwick D. A2 Tintinalli, Judith E. A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Stapczynski, J. Stephan A2 Cline, David M. A2 Thomas, Stephen H. SR Print(0) ID 1166531610 T1 Low-Probability Acute Coronary Syndrome T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260019933 LK accessmedicine.mhmedical.com/content.aspx?aid=1166531610 RD 2024/04/24 AB Of ED patients with undifferentiated chest pain, 7% will have ECG findings consistent with acute ischemia or infarction, and 6% to 10% of those in whom cardiac markers are ordered will have initially positive results.1 The remaining patients who do not have diagnostic ECG changes or initially positive cardiac marker results have low-probability or possible acute coronary syndrome (ACS; either infarction or ischemia including unstable angina pectoris). The evaluation of those with possible ACS costs approximately $10 billion to $12 billion each year in the United States.2