RT Book, Section
A1 Abella, Benjamin S.
A1 Bobrow, Bentley J.
A2 Tintinalli, Judith E.
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Stapczynski, J. Stephan
A2 Cline, David M.
A2 Thomas, Stephen H.
SR Print(0)
ID 1166528070
T1 Post–Cardiac Arrest Syndrome
T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260019933
LK accessmedicine.mhmedical.com/content.aspx?aid=1166528070
RD 2024/04/25
AB Sudden  cardiac  arrest  represents  one  of  the  most  time-sensitive  diseases  in  the  practice  of  emergency  medicine,  requiring  prompt  recognition  and  rapid  delivery  of  resuscitative  care,  including  high-quality  CPR,  early  defibrillation  when  appropriate,  and  appropriate  airway  management.1  Even  with  these  interventions,  aggregate  survival  to  hospital  discharge  is  less  than  20%  in  most  communities  and  hospital  systems.2,3  Among  survivors,  neurologic  injury  is  common  (present  in  up  to  50%  of  survivors)  and  widely  varied,  ranging  from  subtle  memory  deficits  to  persistent  vegetative  state.4,5  This  chapter  focuses  on  the  pathophysiology  of  ischemia-reperfusion  injury  and  the  provision  of  targeted  temperature  management,  also  called  therapeutic  hypothermia.6