RT Book, Section
A1 Riedel, Stefan
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 Sakanari, Judy A.
A1 Hotez, Peter
A1 Mejia, Rojelio
SR Print(0)
ID 1163281629
T1 Antimicrobial Chemotherapy
T2 Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260012026
LK accessmedicine.mhmedical.com/content.aspx?aid=1163281629
RD 2024/04/24
AB Drugs  have  been  used  for  the  treatment  of  infectious  diseases  since  the  17th  century  (eg,  quinine  for  malaria  and  emetine  for  amebiasis);  however,  chemotherapy  as  a  science  began  in  the  first  decade  of  the  20th  century  with  understanding  of  the  principles  of  selective  toxicity,  the  specific  chemical  relationships  between  microbial  pathogens  and  drugs,  the  development  of  drug  resistance,  and  the  role  of  combined  therapy.  Experiments  by  the  German  physician  and  scientist  Paul  Erlich  led  to  the  arsphenamines  for  syphilis,  the  first  planned  chemotherapeutic  regimen.