RT Book, Section A1 Pandya, Amit G. A1 Rivas, Shelly A2 Kelly, A. Paul A2 Taylor, Susan C. A2 Lim, Henry W. A2 Serrano, Ana Maria Anido SR Print(0) ID 1161547395 T1 Melasma T2 Taylor and Kelly's Dermatology for Skin of Color, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071805520 LK accessmedicine.mhmedical.com/content.aspx?aid=1161547395 RD 2024/03/29 AB KEY POINTSMelasma is an acquired, relapsing condition of bilateral facial hypermelanosis.Melasma predominantly affects women with skin of color.An association exists with exposure to ultraviolet radiation, hormonal influences, and genetic predisposition, although the exact cause remains unknown.Melasma negatively affects quality of life and can be socially stigmatizing.First-line therapy entails sun protection and sun avoidance in conjunction with topical depigmenting agents.The use of chemical peels, laser and light therapies should be reserved for refractory cases and used with caution in patients with skin of color to reduce the risk of postinflammatory hyperpigmentation.