RT Book, Section
A1 Kelly, A. Paul
A1 Bayat, Ardeshir
A2 Kelly, A. Paul
A2 Taylor, Susan C.
A2 Lim, Henry W.
A2 Serrano, Ana Maria Anido
SR Print(0)
ID 1161545979
T1 Keloids
T2 Taylor and Kelly's Dermatology for Skin of Color, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071805520
LK accessmedicine.mhmedical.com/content.aspx?aid=1161545979
RD 2024/04/19
AB KEY  POINTSKeloid  disease  is  a  significant  clinical  problem  for  patients  with  skin  of  color.Keloid  scars  are  overgrowths  of  dense  fibrous  tissue  which  develop  as  a  result  of  a  cutaneous  injury  and  invade  the  healthy  tissue  in  the  area  surrounding  the  injury.Hypertrophic  scars  are  also  overgrowths  of  fibrous  tissue,  but  in  contrast  to  keloids,  they  usually  stay  within  the  confines  of  the  precipitating  cutaneous  injury.Keloids  differ  from  hypertrophic  scars  in  their  metabolic  activity  and  collagen  turnover.Many  theories  have  been  advanced  to  explain  the  etiology  of  keloids,  although  none  have  been  substantiated.  However,  it  can  be  said  that  there  is  a  familial  tendency  of  keloid  susceptibility.  This  hereditary  tendency  is  more  common  in  patients  with  skin  of  color.Although  keloids  may  be  found  anywhere  on  the  body,  they  tend  to  have  a  regional  predilection,  occurring  most  often  on  the  ears,  anterior  chest,  upper  back,  and  shoulders.Although  rare,  keloids  may  develop  on  the  genitalia,  palms  and  soles,  mucous  membranes,  tongue,  and  even  cornea.