RT Book, Section A1 Brockmeyer, Norbert H. A1 Lautenschlager, Stephan A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161341526 T1 Lymphogranuloma Venereum T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK accessmedicine.mhmedical.com/content.aspx?aid=1161341526 RD 2024/04/17 AB AT-A-GLANCELymphogranuloma venereum is a sexually transmitted infection caused by L serovars (serologic variants) of Chlamydia trachomatis.Endemic in Africa, Southeast Asia, and South and Central America, and rare in developed countries.Outbreaks have occurred among men who have sex with men in Europe, Australia, and North America.Clinically manifests as inguinal and anorectal syndromes, in 3 stages.Hematogenous spread with manifestations of systemic infection.Diagnosis is by identification of organism and by serology or genotyping.Doxycycline or azithromycin (second-line) treatment is curative if given early in the infection course.