RT Book, Section
A1 Lipworth, Adam D.
A1 Freeman, Esther E.
A1 Saavedra, Arturo P.
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161340945
T1 Cutaneous Manifestations of HIV and Human T-Lymphotropic Virus
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK accessmedicine.mhmedical.com/content.aspx?aid=1161340945
RD 2024/09/19
AB AT-A-GLANCEHIV  is  a  retrovirus  that  causes  immune  suppression  and  dysregulation  primarily  via  depletion  of  CD4+  lymphocytes  and  CD4+  cells  of  monocytic  lineage.In  spite  of  better  screening  programs,  availability  of  antiretroviral  therapy  (ART),  and  improved  side-effect  profiles,  new  infections  continue  to  be  documented.The  range  of  dermatologic  complications  seen  in  HIV/AIDS  relates  to  the  evolving  immunologic  state  of  the  patient,  specific  viral  characteristics  of  the  serotype  causing  infection,  the  period  of  time  from  infection  to  dermatologic  complication,  and  the  length  of  antiretroviral  treatment.Acute  HIV  infection  presents  as  a  mononucleosis-like  syndrome  that  can  include  a  morbilliform  exanthem  3  to  6  weeks  after  infection  with  HIV.In  resource-limited  areas,  untreated  infection  may  lead  to  progressive  dermatologic  disease.In  reconstituted  individuals  and  long-term  viral  suppression,  sun-induced  neoplasia  and  viral-induced  neoplasia  are  significant  burdens.