RT Book, Section A1 Sterling, Jane C. A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161340736 T1 Human Papillomavirus Infections T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK accessmedicine.mhmedical.com/content.aspx?aid=1161340736 RD 2024/03/28 AB AT-A-GLANCEHuman papillomavirus (HPV) has a worldwide occurrence, affecting people of all ages and all races. It is most common in children and young adults.There are more than 150 genotypes of HPV, with some regional specificity. Low-risk types cause warts; high-risk types are associated with intraepithelial neoplasia and malignancy.The lesions are well-defined, raised papules or plaques with a rough or hard surface, usually without inflammation.The lesions are most common on the hands or feet, but any skin site may be affected, including the lower genital or oral mucosa.Treatments include destructive, antiviral, antiproliferative, and immunologic modalities.