RT Book, Section
A1 Tang, Jean Y.
A1 Epstein, Jr., Ervin H.
A1 Oro, Anthony E.
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161335298
T1 Basal Cell Carcinoma and Basal Cell Nevus Syndrome
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK accessmedicine.mhmedical.com/content.aspx?aid=1161335298
RD 2024/04/20
AB AT-A-GLANCEBasal  cell  carcinomas  (BCCs)  are  the  most  common  cancers  in  humans.  All  BCCs  have  mutations  activating  the  Hedgehog  signaling  pathway.BCCs  are  caused  by  exposure  to  ultraviolet  light  and  are  associated  with  PTCH1  gene  mutation  in  most  cases.BCCs  are  locally  destructive  and  rarely  metastatic.BCCs  are  primarily  treated  by  surgical  excision,  electrodesiccation  and  curettage,  Mohs  micrographic  surgery,  and  topical  agents.