RT Book, Section
A1 Vandergriff, Travis
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161327183
T1 Hydroa Vacciniforme
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK accessmedicine.mhmedical.com/content.aspx?aid=1161327183
RD 2024/04/25
AB AT-A-GLANCEA  rare,  chronic,  scarring  photodermatosis  sometimes  associated  with  Epstein-Barr  virus  infection.Characterized  by  recurrent  sunlight-induced  crops  of  papulovesicles  and  vesicles,  most  commonly  on  the  face  and  dorsa  of  the  hands.Onset  commonly  in  childhood,  remitting  most  often  at  puberty.May  be  a  scarring  variant  of  polymorphic  light  eruption.Focal  intraepidermal  vesiculation,  reticular  degeneration  of  the  epidermis,  epidermal  and  upper  dermal  necrosis,  and  sometimes  ulceration  are  typical  histologic  changes.Avoidance  of  ultraviolet  radiation  including  the  use  of  broad-spectrum  sunscreens  is  the  only  established  therapy,  but  there  may  be  a  role  for  antivirals.A  severe,  often  fatal  lymphoma  resembling  hydroa  vacciniforme  is  distinguished  by  fever,  facial  edema,  and  systemic  symptoms.