RT Book, Section A1 Goh, Carolyn A1 Cheng, Carol A1 Agak, George A1 Zaenglein, Andrea L. A1 Graber, Emmy M. A1 Thiboutot, Diane M. A1 Kim, Jenny A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161325229 T1 Acne Vulgaris T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK accessmedicine.mhmedical.com/content.aspx?aid=1161325229 RD 2024/04/19 AB AT-A-GLANCEAcne vulgaris is a common disorder of the pilosebaceous unit.There are four key elements of pathogenesis: (1) follicular epidermal hyperproliferation, (2) sebum production, (3) the presence and activity of Propionibacterium acnes, and (4) inflammation and immune response.Clinical features include comedones, papules, pustules, and nodules on the face, chest, and back.Treatment often includes combinations of oral and topical agents such as antimicrobials, retinoids, and hormonal agents. Laser and light sources are additional treatment options.