RT Book, Section
A1 Schieke, Stefan M.
A1 Wood, Gary S.
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161323249
T1 Parapsoriasis and Pityriasis Lichenoides
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK accessmedicine.mhmedical.com/content.aspx?aid=1161323249
RD 2024/04/16
AB AT-A-GLANCEAlso  known  as  parapsoriasis  en  plaques.Parapsoriasis  occurs  worldwide  and  affects  mainly  adults.Large-plaque  parapsoriasis  (LPP)  and  small-plaque  parapsoriasis  (SPP)  are  recognized.Large  and  small  “plaque”  lesions  actually  present  as  flat  patches  rather  than  infiltrated  plaques.Lesions  are  chronic  and  favor  non–sun-exposed  skin;  LPP  may  be  poikilodermatous.Pathology  consists  of  superficial,  mostly  CD4+  T-cell  infiltrate;  dominant  clonality  is  more  common  in  LPP  than  in  SPP.LPP  appears  to  exist  on  a  continuum  with  patch-stage  mycosis  fungoides  (MF)  and  progresses  to  overt  MF  at  a  rate  of  approximately  10%  per  decade.SPP  has  minimal  risk  of  progression  to  overt  MF  in  the  experience  of  most  experts.Treatment  options  include  topical  corticosteroids;  ultraviolet  B  irradiation,  and  psoralen  and  ultraviolet  A  irradiation;  excimer  laser;  and  topical  cytotoxic  drugs.