RT Book, Section A1 Silverberg, Jonathan I. A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161322374 T1 Nummular Eczema, Lichen Simplex Chronicus, and Prurigo Nodularis T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK accessmedicine.mhmedical.com/content.aspx?aid=1161322374 RD 2024/10/06 AB AT-A-GLANCENummular eczema:Also known as nummular dermatitis and discoid eczema.A chronic inflammatory skin disorder of unknown etiology.Papules and papulovesicles coalesce to form nummular plaques with oozing, crust, and scale.Most common sites of involvement are upper extremities in men and women, particularly the dorsal hands in women, and the lower extremities in men.Pathology may show acute, subacute, or chronic eczema.Lichen simplex chronicusA chronic, severely pruritic disorder characterized by one or more lichenified plaques.Most common sites of involvement are scalp, nape of neck, extensor aspects of extremities, ankles, and anogenital area.Pathology consists of hyperkeratosis, hypergranulosis, psoriasiform epidermal hyperplasia, and thickened papillary dermal collagen.Prurigo nodularisAlso known as prurigo, picker’s nodules, or nodular prurigo of Hyde.A pruritic disorder that runs a chronic course.Hyperkeratotic firm nodules vary in size from 0.5 to 3.0 cm and may be excoriated.Associations include atopic dermatitis and systemic causes of pruritus.Pathology consists of hyperkeratosis, hypergranulosis, psoriasiform epidermal hyperplasia, thickened papillary dermal collagen, and characteristic neural hypertrophy.