RT Book, Section A1 Sundheimer, Lauren W. A1 Nathan, Lauren A2 DeCherney, Alan H. A2 Nathan, Lauren A2 Laufer, Neri A2 Roman, Ashley S. SR Print(0) ID 1159962734 T1 Menopause & Postmenopause T2 CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 12e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071833905 LK accessmedicine.mhmedical.com/content.aspx?aid=1159962734 RD 2024/04/25 AB ESSENTIALS OF DIAGNOSISNatural menopause diagnosed after 12 months of amenorrhea with no obvious pathologic causeAverage age 51 years• Estradiol < 20 pg/mL and follicle-stimulating hormone level 21–100 mU/mL helpful in establishing the diagnosisInduced menopause is defined as permanent cessation of menstruation after bilateral oophorectomy or ablation of ovarian function (ie, by chemotherapy or radiation)Premature menopause defined as menopause reached at or before age 40 and can be natural or inducedPerimenopause/menopause transition defined by menstrual cycle and hormonal changes that occur a few years before and 12 months after the final menstrual period resulting from natural menopauseMay be associated with vasomotor symptoms, sleep disturbance, and vaginal/urinary symptoms