RT Book, Section A1 Nayeri, Unzila A1 Thung, Stephen F. A2 DeCherney, Alan H. A2 Nathan, Lauren A2 Laufer, Neri A2 Roman, Ashley S. SR Print(0) ID 1159953944 T1 Congenital Fetal Infections T2 CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 12e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071833905 LK accessmedicine.mhmedical.com/content.aspx?aid=1159953944 RD 2024/04/19 AB ESSENTIALS OF DIAGNOSISCaused by parvovirus B19, a single-stranded DNA virusClinical manifestations: commonly asymptomatic, erythema infectiosum, systemic symptoms (fever, arthropathy, malaise), or aplastic crisesComplications in pregnancy: fetal demise, fetal anemia, hydrops fetalisDiagnosis: serologic tests (immunoglobulin [Ig] G and IgM antibodies); serum viral DNA polymerase chain reactionAntenatal sonographic findings: fetal anemia, hydrops, elevated middle cerebral artery peak systolic velocityFetal diagnosis: cordocentesisFetal treatment: intrauterine blood transfusion