RT Book, Section
A1 Barrett, Kim E.
A1 Barman, Susan M.
A1 Brooks, Heddwen L.
A1 Yuan, Jason X.-J.
SR Print(0)
ID 1159052593
T1 Basic Concepts of Endocrine Regulation
T2 Ganong's Review of Medical Physiology, 26e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260122404
LK accessmedicine.mhmedical.com/content.aspx?aid=1159052593
RD 2024/04/20
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Describe  hormones  and  their  contribution  to  whole  body  homeostatic  mechanisms.Understand  the  chemical  nature  of  different  classes  of  hormones  and  how  this  determines  their  mechanism  of  action  on  target  cells.  Contrast  membrane  bound  and  intracellular  hormone  receptors  and  understand  the  principles  of  desensitization,  down-regulation,  and  inactivation.Define  how  hormones  are  synthesized  and  secreted  by  cells  of  endocrine  glands,  including  how  peptide  hormones  are  cleaved  from  longer  precursors.Understand  the  effects  of  plasma  hormone  binding  proteins  (thyroid  and  steroid  hormones)  on  the  availability  of  hormones  to  their  sites  of  action,  and  on  the  mechanisms  that  regulate  hormone  secretion.Explain  the  principles  of  feedback  control  (negative  and  positive)  of  hormone  secretion.Understand  the  principles  governing  disease  states  that  result  from  over-  or  under-production  of  key  hormones.